Ifeni yedeskithophu ye-USB wuhlobo lwefeni encane enikwa amandla yimbobo ye-USB, ikwenze kube lula ukusetshenziswa nekhompuyutha ephathekayo, ikhompyutha yedeskithophu, nanoma iyiphi enye idivayisi enembobo ye-USB. Laba balandeli bakhelwe ukuhlala edeskini noma kwenye indawo eyisicaba futhi banikeze umoya opholile ozokwehlisa. Ngokuvamile anomklamo ohlangene futhi angalungiswa ukuze aqondise ukugeleza komoya endaweni ethile. Amanye amamodeli anikezela ngezilungiselelo zejubane ezilungisekayo, ukuze ukwazi ukulawula ukushuba kokugeleza komoya. Abalandeli bedeski le-USB bayisixazululo esihle kubantu abasebenza edeskini isikhathi eside noma abadinga ukupholisa phansi endaweni efudumele, njengoba kulula ukusethwa nokusetshenziswa, futhi abadingi umthombo wamandla ohlukile.